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KMID : 0061119810090000156
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Bulletin of the Clinical Research Institute
1981 Volume.9 No. 0 p.156 ~ p.156
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The Effect of Renal Hypothermia for the Interruption of Renal Blood Flow in Dogs
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Cho Dai-Haing
Lim Soo-Kil
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Abstract
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We observed the histological changes of the renal tissue by temporary interruption of renal blood flow without (Group A) and with renal hypothermia by iced9-aline slush method(Group B) in 20 dogs.
The renal blood flow was interrupted for 20, 40, 60, 80 and 100 minutes on both groups. The histological changes of renal tissue were observed for the glomerulus, blood vessels and renal tubules.
Results were as follows:
1) Glomerular congestion was observed in Group A in 40 minutes after the initiation of experiment.
2) Renal vascular congestion was observed in Group A in 40 minutes after the interruption of renal blood flow and 60 minutes inGroup B.
3) Desquamation of renal tubular epithelium, vacuole formation and dilatation of renal tubular were observed in GroupA in 40 minutes after the interruption of renal blood flow and 60 minutes in Group B.
4) Renal tubular necrosis was observed in Group A in 60 minutes and in Group B in 80 minutes after the interruption of renal blood flow but it showed.
5) The congestion of glomerulus began to occur at 40 minutes of the interruption of renal blood flow in Group A, and at 60 minutes of the interruption of renal blood flow in Group B. However, there was no great difference Iin its changes in both groups.
6) The congestion of renal vessels began to occur at 40 minutes of the interruption of renal blood flow in Group A, and at 60 minutes in Group B, and overall changes were a little more excessive in Group A than in Group B.
7) The changes of tubules such as focal necrosis of tubular epithelium, vacuole formation, tubular dilatation, etc. began to occur first at 40 minutes in Group A and at 60 minutes in Group B, and the above changes began to be more excessive from 60 minutes in Group A and from 80 minutes in Group B.
8) The focal necrosis of tubules began to occur from 60 minutes in Group A, and from 80 minutes in Group B.
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